An Australian scientist has come up with a new method of dispensing potent chemicals that are found in Vitamin E, which might be vital in treating pancreatic cancer and fatty liver disease. Health experts have said that chemicals that are known as tocotrienols (T3s) might work as anti-inflammatory agents. It can prevent scarring and fat accumulation. As per the report, T3s have delivered promising results when they have been tested on rats initially. At that time, they have been proved to be less effective in human trials. However, later, Dr. Glenn Tong has found out that rats have been showing better results because they have been chewing the drugs properly before swallowing them.
He has said that it might be the most direct way of delivering the drug as it goes directly into the bloodstream without going via the gut and liver first. Now, Dr. Glenn Tong has tried the same thing in humans and has come up with a new tool to deliver the T3s under the tongue. He has said that Vitamin E is generally used to keep skin healthy and clear. It is good for immune function as well. He has said that the potential of this vitamin is quite huge in treating some terminal diseases.
Dr. Glenn Tong has developed this delivery tool under his company called Azure Health Technology. He has already secured patents for the delivery technology in some of the major markets across the world such as the US, the EU, Japan, and China. He is all set to embark on Phase two clinical trials of tocotrienols (T3s) that need to be given to patients who are dealing with pancreatic cancer and fatty liver disease. The drugs will be delivered under the tongue of the participants in the clinical trials. Dr. Glenn Tong has said T3s have not been tried in this manner ever before.
Health experts have said that at present, there is no effective treatment for fatty liver disease. At the same time, currently available treatments for pancreatic cancer, do not offer much relief to the patients. Existing treatments for pancreatic cancer that have been approved by the regulatory authorities do not enhance the quality of life of patients who are dealing with the dreaded disease. These approved treatments for pancreatic cancer are not very effective in increasing the survival rate in patients, said the experts.
Scientists who are involved in phase two clinical trials of this potent chemical that is found in Vitamin E have said that the findings of the trials will be available within two years. On the Other hand, the officials from the US Food and Drug Administration (FDA) have said that they might speed up the approval process for T3 drugs that might be quite essential for treating pancreatic cancer and fatty liver disease. Dr. Glenn Tong has claimed that tocotrienols (T3s) drugs can be effective against cancer cells as they might be able to trigger cell cycle death. The T3 drugs might be able to prevent metastasis as well, which can lead cancer to spread through the body.
The company Azure Health Technology has raised a total fund of $2.25 million through an initial public offering (IPO) to partially sponsor the two trials of T3 drugs. The officials of the company are planning to list on the Australian Securities Exchange (ASX) as well for further funding later this month. Dr. Glenn Tong has said that if everything goes as per the plan, the new drugs for treating pancreatic cancer and fatty liver disease will be available in the market in the next three to four years.